Ursosan: Instructions, how to take it correctly, the duration of the course, how much does it start to act?

Read the article about Ursosan. It has a lot of useful information about the readings of the drug, its contraindications, duration of administration, etc.

Ursosan belongs to the group of hepatoprotectors, increases the protective properties of the liver to negative influences, helps regeneration and prevents cell destruction. It also has a choleretic effect and dissolves stones in the gall bladder. Therefore, it is very popular among patients with similar diagnoses.

Read in another article on our website article about stones in the gall bladder. You will find out what symptoms are in such a state, what nutrition and treatment should be.

Read more about this drug below. How to take it correctly? What is the duration of the course? Read further.

Ursosan 250, 500 mg: Instructions for use

Active substance: ursodexicoic acid.

Read more instructions for use. Ursosan is produced 250 and 500 mg Two types of table:

Pharmacological properties:

• Ursosan is a hepatoprotective drug.
• It has choleretic, golitolytic, lipidemic (reduces the concentration of lipids), hypocholesterol (reduces cholesterol content), immunomodulating properties.
• Due to its high polarity, it connects to the liver cells and epithelium, embedded in the membranes, and protects them from damage and toxic effects.
• It forms non -toxic compounds with toxic acids of bile - micelles. This helps reduce cell damage in cholestatic pathologies, as well as in reflux gastritis and reflux esophagitis (associated with the result of the contents of the gallbladder in the stomach and esophagus).

Significantly reduces the quantitative content of cholesterol in the gall element, inhibiting absorption and suppressing its synthesis. This property contributes to the dissolution of cholesterol calculi inside the gallbladder and prevents their formation.

Enhances the biological secretion of the pancreas, promotes the fall of glucose levels in human biological fluids.

Immunomodulation of Ursodex. Acids (UDC) consists in inhibition of antigens in the liver cells and in increasing the activity of lymphocytic cells. Reduces the process of growth of fibrous tissue. UDCC is also involved in the synthesis of interleukin-2 protein and in the inhibition of immunoglobulins.

Pharmacokinetics:

• The absorption of the drug occurs in some sections of the ileum and in the junk. The degree of resorption is 60-80%.
• The maximum concentration is achieved after 1-3 hours.
• It is associated with protein cells of blood plasma almost completely ( 99%).
• With blood flow enters the placenta.
• With prolonged admission of UDHK, it is converted to bile K-Tu.
• Metabolized in the hepatic organ. The initial clearance reaches 60%. The formed substances are excreted with the bile mixture ( 50-70%).
• Some number of UDCH is broken down in the large intestine, the process of absorption occurs in the same place.
• It enters the liver with blood and again goes through the bile ducts.

Special recommendations:

In the process of cure (dissolution) of bile deposits, it should be borne in mind that it is possible to drink ursosan only to dissolve cholesterol calculi, parameters no more than 20 mm.

When curing ursosan housing and communal services (gall-kamen. Diseases), it is important to monitor transaminase activity:

• For this, at the beginning of the cure process ( for 3 months) blood biochemistry is carried out monthly, later the analysis must be carried out every every 100 days.
• Once at 6 months It is necessary to do an ultrasound, controlling the treatment process.

At the end of the treatment, taking the medicine is recommended for another three months to dissolve small residues that are not visible during ultrasound examination.

Ursosan: Indications

Remember: Do not self -medicate! Even if you know the diagnosis, you should not prescribe treatment for yourself. All drugs are prescribed only by the doctor.

Indications for the reception of Ursosan:

• Chronic. Hepatitis of different genesis (toxic and medicinal).
• Gallstone disease, which occurs without complications, for preventive measures after cholecystectomy, as preventive measures, so that new dense delayed ones are not formed.
• Cholestatic pathologies: biliary cirrhosis (primary), sclerosing cholangitis (primary), cystic fibrosis (cystic fibrosis).
• Fat disease - hepatosis - (non -alcohol), steatogepatitis.
• Reflux gastritis, reflux esophagitis, colitis.
• Discinesia ZhVP (gall-output. Paths).
• Alcohol. Hepatic pathology.
• Chronic. Viral hepatitis.
• Liver hemangioma.
• Hepatoprotection for cancer patients underwent chemotherapy, as well as due to taking some antibiotics, antiviral agents, oral contraceptives, etc.

You also need to know about contraindications for taking the drug. Read more more.

Ursosan: Contraindications

If there are allergic reactions to active and additional components of the tablets, then it is worth abandoning their reception and come to a consultation with a specialist. Other contraindications of Ursosan:

• Serious disorders of the gallbladder
• Cirrhosis (with pathological changes)
• Calcinated stones
• Inflammatory processes in the bile flow channels and in the "pipes" of the intestine

Functional disorders of the liver, kidneys and pancreas. Generations - these conditions are also a ban on taking capsules or tablets.

Side effects of Ursosan

From the gastrointestinal organs: The most common side effect of Ursosan is diarrhea, changes in the consistency of the chair. Rarely - nausea, vomiting. The complaints of patients about pain in the upper bosses were noted (extremely rarely).

Liver and bile. ways: Calcinating of deposits was rarely fixed. With primary biliary cirrhosis, de compensation may not often occur. After stopping the use of capsules or tablets, regression occurs.

The skin: urticaria - rarely.

With an overdose, diarrhea is not excluded. The probability of other manifestations is small. If intestinal disorders occur, taking the drug must be suspended and consult a doctor. Treatment of diarrhea - in symptoms.

Ursosan interaction with other drugs

It is forbidden to take with antacids, as they reduce the absorption of UDC. Some drugs increase golitiasis and act with the opposite effect. These include:

• Clophibrat
• Hormonal contraceptives
• Neomycin

The interaction of Ursosan with other drugs does not bring any unpleasant symptoms or conditions.

Ursosan: reception during pregnancy and breastfeeding

Since Ursosan penetrates through the placenta, there is a risk of side effects on the fetus. Therefore, reception during pregnancy is contraindicated. It is also worth noting that with the urgent need for the treatment of a nursing mother, it is advisable to stop breastfeeding.

How to take ursosan correctly: the duration of the course

The correct use of Ursosan is orally during or immediately after eating. Drink with liquid. The duration of the course is from several weeks to several years. To some patients, Ursosan's reception is prescribed for life. Dosage and duration of the course is prescribed by a doctor.

Duration of administration and dose in some diseases:

• Hepatitis treatment of all genes, alcoholic and non -alcoholic fats. diseases, steatogepatitis lasts from six months up to 1 yearSometimes the course is prolonged. Assign to accept 2-3 p. In day. 10-15 mg/kg.
• With cholestatic diseases The course lasts from six months to several years. The first 3 months. Reception of capsules and tablets must be separated by a daily basis. Dose. If the blood biochemistry shows improvements, then you can switch to a single medication before bedtime. The dosage will be 12-15 mg/kg, maybe life is increased up to 30 mg/kg.
• Diskinesia treat from 2 weeks up to several months. Based on the results of treatment, the doctor may prescribe a repetition of the course. The dose for two daily methods should be 10 mg/kg.
• In reflux diseases, the course lasts from 2 weeks up to six months ( sometimes up to 2 years). Take once at night. Dosage - 250 mg.

Here's how you can calculate the daily dose of this drug for the patient:

• For example, with the weight of the patient in 60 kgIf there is enough dosage 10 mg/kg, then the doctor will prescribe 2 capsules or 1 tablet.

To dissolve deposits in the gall bladder, the medicine is taken overnight. The course may last from 3 months to 1 year. If an improvement does not occur after a year, then the drug is canceled. Dose 10 mg/kgSometimes a doctor can increase it.

Important: If the doctor has prescribed the intake of this drug, and you refuse to be treated, then this can lead to the removal of the gallbladder. The fact is that stones can increase in size and will interfere with the liver and other gastrointestinal organs. Also read on our website an article about life after removing the gallbladder. It is better not to bring your body to such a state and follow all the recommendations of a medical worker.

Ursosan: How long does it start to act?

Ursosan begins to act after 1-3 hours After entering the body. Some patients feel that their condition has become better during the first weeks of admission. The longer the course, the more UDHK replaces toxic acids. The dissolution of bile deposits occurs over time.

Important: The dosage and duration of treatment should be prescribed only by a doctor.

Ursosan 250 mg: analogues

Analogs u rSOSANAN (250 mg) They must also have ursodeoxichole acid (UDC) in their composition. Drugs that can replace these tablets:

• Ursokhol
• LyDADEX
• Eshol
• Ursodez
• Ursodex
• Ursofalk
• Ursoliv et al.

Only a doctor should also prescribe analogues, since in addition to UDC, other active components or substances can be added to them.

Ursosan: reviews

If the doctor prescribes this drug to you, and you do not know or not and whether it will help you, then read the reviews of other people who are successfully treated with it.

Zhanna, 38 years old

It all started with pain in the right hypochondrium. I turned to the clinic. There were diagnosed dense deposits in the gall bladder. They were still small, up to 6 mm, but there is little pleasant anyway. Ursosan was appointed two caps. before bedtime. I began the treatment with all responsibility. I followed the strict diet table No. 5 and I drank Ursosan for three months. Twice during this time she made a blood biochemistry, which showed that treatment can be continued. Three months later, during an ultrasound of the gall bladder, they told me: “Everything is normal here. What bothers you? " The stones disappeared. Honestly, I did not even count on such a quick effect.

Julia, 60 years old

I have long suffered by discinesia, the outflow of bile contents is impaired, and because of this, bilirubin is increased. It hurts in the right side, sick, constant heartburn. Only Ursosan helps. I drink courses, at least 3 months. About 2 p. in year. The condition improves, pain disappears and bilirubin decreases. From side effects, diarrhea sometimes occurs. A very good drug. True, with a long course of treatment, it turns out not cheap. This is the only negative.

Sergey, 41 years old

When a physical examination was held, they found problems with the liver. He turned to a gastroenterologist, examined, prescribed Ursosan. Immediately bought the largest package, in which 100 capsules are more economical. He began to accept. Immediately began the intestinal disorder. He told the doctor, he reduced the dose. For a week I drank 1 capsule per day. The problem with diarrhea disappeared, and I returned to the initial dose. I have been drinking the medicine for about 4 months, I feel the result: drowsiness has disappeared, bilirubin has decreased. I continue treatment.

Only a doctor can prescribe a medication of Ursosan. There are contraindications. Children are prescribed with caution. Treatment of a child should take place under careful medical supervision. Good luck!

Video: Ursosan (capsules, tablets) - Instructions for use

Video: Ursosan. Protection of the liver, health of the gallbladder. Review of the drug

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