When is it better to drink statins: in the morning or evening, before meals or after?

Incorrect nutrition leads to a high level of cholesterol in the blood. Many will say that there is nothing wrong with this, but in reality this is not so, since a large amount of this substance contributes to atherosclerosis and damage to the vascular system.

Content

At the beginning, the wall of the vessel is damaged. It is there that cholesterol and fats rush. As a result, a plaque is formed, which overlaps the vascular clearance, which leads to circulatory disorders. If the plaque forms in the brain, then a stroke occurs, and if in the heart - a heart attack. To avoid serious health problems, special drugs are prescribed that are part of the statin group.

What are statins?

Statins are drugs that reduce cholesterol.

In most cases, doctors prescribe these drugs for the prevention of cardiovascular complications of atherosclerosis:

coronary, coronary heart disease;
infarction;
stroke.

Statins, unlike other drugs, are taken according to the administration of drugs. When to take statins, in the morning or in the evening, before or after eating?

The action of statins on the body

Statins are also called inhibitors of the GMG-CoA reductase. The second name reflects their principle of action. The drugs have the ability block One of the enzymes, without which the chemical compound of cholesterol is impossible.
Sterol has a bad reputation, but the human body needs it. This is a mandatory component of cell membranes, the main material for the synthesis of vitamin D and steroid hormones.
To prevent a deficiency of this substance, the body finds spare sources of cholesterol. For example, statins increase the concentration of “useful” lipoproteins with a high density of HDL, which helps to improve the walls of blood vessels and does not allow blood clots.

What time is it better to take statins?

There are many opinions when it is better to take statins. But each medicinal drug is instructed where it is spelled out, how and when to drink them.

Cholesterol synthesis in large quantities occurs at night. During this period, the concentration of statin in the blood should be high. The drug blocks the largest number of cholesterol formation and most effectively reduces its concentration.

Each remedy has a different half -life period:

Lovastatin - 3 hours;
Simvastatin - 2 hours;
Fluvastatin - 7 hours;
Piavastatin - 9 hours;
Atorvastatin - 14 hours;
Rosuvastatin - 19 hours.

Statins with the smallest period of excretion should be taken in the evening, otherwise a small amount of the drug will remain by the time of active cholesterol. Statins with a large period of excretion, for example, atorvastatin or rosuvastatin are removed from the body slowly, so they can be taken at any time.

According to the studies of the effects of drugs at the level of triglycerides, total cholesterol and HDLs, no reliable differences between morning and evening techniques were found.
The analysis of statins with the least period of excretion did not show significant differences between taking the drug in the morning and evening. But by changing the total cholesterol and LDL, it was revealed that the evening reception is more effective.
Studies of statins with prolonged excretion of the drug also did not show a significant difference in cholesterol and LDL. But evening doses were more effective in terms of LDP.
There are exceptions, such as Pyavastatin. The drug occupies an intermediate position. But the instructions for use indicate that this tablet should be drunk before bedtime.

How to take statins: before meals or after?

For suction, food does not have any significant effect. The diet plays a big role. The effectiveness of statins without much difficulty with food can be reduced to naught. To do this, it is enough to add foods with a high cholesterol, trans fats, saturated fats, sugar to the menu.
Means do not affect the absorption of food sterol. A large amount of cholesterol in the body compensates for the lack of synthesis using food. And as a result, the level of sterol does not decrease.
A prerequisite is exclusion from the diet of alcoholic beverageswho deliver a strong blow to the liver. To this is added a medication. Smoking also negatively affects the decrease in cholesterol, since nicotine damages the vascular system.
During the techniques of statins of the 1-3th generation, use is prohibited grapefruit juice. It includes substances that block an enzyme-carrier that is necessary for eliminating the drug from the body. The amount of medicine in the blood increases, which provokes the appearance of side effects.
An exception is the drug Lovastatin. It is accepted precisely during dinner.

How to take statins: recommendations

During the use of drugs that reduce cholesterol, you should adhere to the following recommendations:

Drink a tablet with only clean water. It is forbidden to do this with such drinks as tea, coffee, juice, milk, etc.
Statins are not chewed, the tablet drinks whole. This increases its action. The notching tablets for division can be broken if necessary, since their composition is allowed by a fractional intake of the drug.
Take the inhibitors of the GMG-KoA reductase without a daily binding is necessary regularly at the same time. Compliance with the graph contributes to a stable concentration of the drug in the blood, which reduces the amount of cholesterol. There will be no positive result if the reception schedule fluctuates.
If the use of statins was missed and more than 12 hours left until the next, drink the medicine as soon as possible. If more time has passed, wait for the usual medication. You do not need to increase the dosage.

It is permissible to separate the tablet

Thus, statins are drugs that reduce blood cholesterol. This medicine is the prevention of cardiovascular diseases. It is accepted in the morning or evening at the same time. According to studies, these drugs can be consumed regardless of food intake.

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