In our article you will learn about the drug "Negram". On the testimony of this antibacterial drug in what cases it is contraindicated and what analogues it can be replaced.
Content
Instructions for use
Neogram belongs to the antibacterial agents of the group hinolonov. Subject to the sensitivity of the microorganism to antibiotics of this group, the "non -ram" provides bacteriostatic (stops the growth and development of microorganism) and bactericidal (leads to the death of bacteria) Action on the pathogen. The antibiotic has an overwhelming effect on the synthesis of proteins necessary for constructing DNA of bacteria, blocking the process polymerization.
“Negram” is active in the fight against those bacteria that are not sensitive to sulfonamide antibacterial agents, as well as to pathogens of salmonellosis, intestinal infections and klebsiellah.
The drug is not active in relation to anaerobic microorganisms and belonging to a group of gram -positive bacteria.
Forms of release
- “Neogram” has only a tablet or capsule form of release and is not available in the form of injections. In each tablet, the content of the active substance is 500 mg
- The main active substance of the drug is navidix acid
- At the time of treatment, this tool is likely to develop resistance (stability) to antibiotics
Indications for use
"Negram" is indicated for use in treatment infectious and inflammatory process in the following diseases:
• The inflammatory process of prostate in men (prostatitis)
• cholecystitis (inflammation of the gallbladder)
• Inflammation of the bladder ( cystitis)
• Urethra inflammation (urethritis)
• infectious diseases of the gastrointestinal tract
• pyelonephritis (purulent inflammation of the kidneys with the release of a large number of leukocytes)
"Negram" dosage
The “non -ram” in the treatment of an adult is prescribed according to the scheme of 2 tablets up to 4 times a day for 1 week. If it is necessary to conduct a longer course of therapy, then the dosage can be transferred to a 1 tablet supporting in an amount of up to 4 times a day.
It should be noted that the drug is contraindicated for pregnant women and with caution is prescribed for women with breastfeeding the baby.
During breastfeeding, the medicine can only be used if the expected effect of use for a nursing mother exceeds the risk of side effects in the child.
"Negram" to children
The appointment of this drug can be started from the age of two. 
The dose for prescribing at the beginning of therapy is 60 mg per kilogram of body weight, then the dosage for maintenance therapy decreases and is 30 mg per kilogram of body weight of the child. Such calculations for treatment are carried out for children of age from 2 to 12 years. The daily dose is divided into 3 or 4 doses.
"Negram" contraindications
Contraindications to the use of this drug are the following diseases and conditions:
• violation of the urinary and filtration function of the kidneys
• Anamnesis epileptic attacks
• Pregnancy
• impaired liver function
• Children under 2 years old
• severe atherosclerosis
• an allergic reaction to the components of the drug
special instructions
If in the process of treatment the child has pain in the joints, this drug should be canceled.
With the manifestation of side effects or violation in the work of the central nervous system, treatment must also be canceled.
During therapy, it is recommended not to be in the sun for a long time.
When passing the analysis of urine for the content of glucose, the indicators can be falsely positive.
If a " Negro»It is used in conjunction with ethanol (drinking alcoholic beverages), this may lead to the inhibition of the nervous system and its oppression. Same effect can cause use with Namygren central drugs.
"Negram" Side effect 
When using the antibacterial agent " Namygren»The following side effects may appear:
• From the part of the central hen-head pain, drowsiness, the perception of color is disturbed, dilopia, increasing intracranial pressure, frequent mood change, convulsions
• from the side of the housing rods, nausea, pain in the stomach, diarrhea, bleeding of the mucous membranes of the intestinal tract, stagnation of bile in the biliary tract and gall bladder
• Allergic reactions to the components of the drug, manifested by itching, skin rashes, swelling
• From the muscle and musculoskeletal system may appear mILCOM, exposure to cartilage fabric of the articular surfaces
• The offensive of renal failure
« Negro"For therapy of the disease, only a doctor can prescribe. Do not self -medicate, so as not to provoke critical health states.
The uncontrolled long -term use of this antibacterial drug can lead to serious consequences:
• Development of thrombocytopenia
• anemia associated with blood loss during bleeding of the mucous membrane of the gastrointestinal tract
• Development leukocytopenia
• To the manifestation of photosensitization of the skin
Interaction "Negram" with other drugs
The drug cannot be used in treatment with nitrofurazidsThis is strictly contraindicated.
Also, it is not necessary to prescribe “Neograms” together with anticoagulants, this can provoke bleeding of the mucous membranes of the gastrointestinal tract.
Reviews
This drug has a positive characteristic in reviews.
According to polls, the drug has 
high efficiency and quickly removes sharp infectious and inflammatory states. Of the side effects that manifested in patients only a sleepy state is mentioned.
We wrote about taking the drug during breastfeeding. The nursing mothers who used this drug noted for treatment that the baby had a chair and changed color. In such cases, it is recommended to give the child bifidum bacteriasince the baby receives part of the drug with mother’s milk and is the likelihood of developing dysbiosis.
Analogs
• Nevgramon-only an analogue that has the same acting substance as the "non -ram"
• Densiture
• Eco -Bol
• Ecocyol
• Tsiprm
• Urinal
“Negram” is not on the sale of representative pharmacies, there are only its substitutes. Any use of antibacterial drugs must be agreed with the attending physician.
The release of the drug in pharmacies is carried out strictly according to the prescription of a doctor with the presence of personal print.
Video: Antibacterial therapy
