"Prednisolone" a powerful anti -inflammatory agent. Let's talk about the aspects of its purpose and the action that the drug has.
Content
« Prednisone» is synthetically synthesized drug rows glucocorticosteroids. Means it has characteristics hydrocortisone and possesses those the same indications to application, what and similar hormonal therapy.
« Prednisone» instructions to application
This analogue hormone it has influence on the protein exchange in body, reducing concentration globulinov in blood. So the same he activates synthesis albuminov liver and buds. Proving influence on the exchange fat, a drug maybe provoke development holisterinemia.
« Prednisone» provides influence on the exchange glucose and capable call high concentration carbohydrate in blood. Provides influence on the bone system, calling demineralization fabrics.
The main thing positive influence drug is his powerful anti -inflammatory effect. He founded on the capabilities oppress release mediators inflammation.
So the same this a drug it has antihistamines properties and reduce swelling per check reduction permeability vascular walls. Substance blocks process synthesis prostaglandinov.
What important at autoimmune diseases very important is effect immunosuppression. A drug provides oppressive action on the proliferation lymphocytes, in particular on the T—lymphocytes.
« Prednisone» forms release
it means it has the following forms release:
• « Prednisone»- ointment for external use
• « Prednisone»- ampoules for intravenous injections
• « Prednisone»- tablets
• « Prednisone»- drops for eye
Each from form release it has definite spectrum diseases, at which a drug accepted on strict testimony doctor.
« Prednisone» indications to application
1. « Prednisone» in ampoules for intravenous injections used for therapy the following pathologies:
• At development acute allergies
• For treatment bronchial asthma in periods exacerbations
• Liquidation shock
• Therapy thyrotoxic crisis and his prevention
• Therapy cirrhosis liver and hepatitis A in acute phase
• Help in treatment renal and liver insufficiency
• Chemical burns organs larynx (with the goal prevention formation rubtsov)
• Treatment rheumatoid arthritis, osteo arthrose defeat and spondylitis
2. « Prednisone» tablet the form shown at:
• Diseases connective fabrics, wearing systemic character
• Diseases joints in acute and chronic forms
• Rheumen in acute phase and rheumatic fever
• Bronchial asthma
• Therapy edema brain
• Congenital pathology kidneys with hypertensive syndrome
• Diseases hematopoies organs, inflammation thyroid glands in subacute form, autoimmune diseases
• Tuberculosis different form, in volume number and meningitis
• Inflammatory diseases lungs in heavy degree
• Oncological disease lungs in complex therapy
• Ulcerative defeat systems Gastrointestinal tract
• Increased content calcium in blood, determined oncosaurium
• Allergic and inflammatory diseases eye
3. « Prednisone» in form ointments designed for external application:
• Neurodermatitis
• Hives
• Dermatitis atopic
• Bursites
• Red lupus discoid the form
• Erytroderma
• Eczema
• Therapy colloidal rubtsov
4. « Prednisone» drops eye applied:
• Inflammatory diseases eye non -infectious genesis
• Injuries eye and after conducting operational interventions
« Prednisone» children
Reception children this drug must pass under strict observation the doctors, conducting well therapy. Dose medicinal funds calculated individually for child isavit from degree severity diseases.
Not assign this a drug to your own to kid on one's own, so how this is maybe bring to heavy complications and deterioration his states.
« Prednisone» dosage
- How it was mentioned previously, dose and duration conducting therapy given remedy doctor appoints individually, based on on the data examinations and anamnesis diseases
- Usually medicine assigned with one -time reception daily doses in morning time, in comparison with familiar rhythm products endogenous hormones
- Or reception held in doubled dose, but through day. If a assigned dose very great, then her can divide on the several receptions, but big her part necessary accept in the morning
- Recommended accept tablet form drug in time breakfast, sackling small quantity water
- At exacerbations diseases adults assign starting dose in 20—30 mg in day, then reducing before supportive in 10 mg. At need initial dose maybe to be before 100 mg
- Children assigned initial dose in calculation before 2 mg on the 1 kg masses bodies, dividing on the 6 receptions, a supporting before 600 mKG on the 1 kg masses bodies
After achievements desired effect dose reduced gradually.
« Prednisone» contraindications
In addition individual intolerance components drug, with caution his costs assign patients cO next violations:
• At Yabzh and 12—persian guts, esophagitis, at peptic ulcer and gastritis
• At availability parasites in body, viral infections, gribkov or bacterial lesions
• At herpes infections, active and lethal forms tuberculosis, at systemic mycose
• Period before and after vaccination
• Diseases cordially—vascular systems
• Diseases endocrine systems (thyroid glands, sugar diabetes and t.d..)
• Renal and liver insufficiency in heavy form
• Children in period growth
• Pregnancy
• Destructive diseases bone systems
« Prednisone» side action
The a drug maybe have big amount side effects:
• Development steroid sugar diabetes and provocation beginning development predisposed sugar diabetes
• Increase level glucose blood
• Development syndrome Insent—Kushenga
• Suppression work adrenal glands
• Delay sexual maturation u teenagers
• Nausea and vomit
• Esophagitis erosive
• Steroid Jay
• Increased gas formation
• Provocation bleeding stomach
• Violation rhythm heart abbreviations
• Hypertension syndrome
• State euphoria
• Violation orientation in space
• Insomnia
• Mental violations
• Convulsive syndrome and head pain
• Increase intraocular pressure
• Losing weight
• Acne rash, striya, rash and itching skin
• Stormy allergic reaction in form shock
• Development syndrome cancellations
Analogs
• Solu—Decortin
• Prednisolone sodium phosphate
• Honey
• Prednisone bufus
• Prednisone sodium phosphate