Features of amoxiclava.
Content
Amoxiclav is a common antibiotic that is used in pediatrics, as well as for therapeutic purposes. However, there are a number of features of using this antibiotic. In this article we will tell you how to accept it.
Amoxiclav: Composition and action
This drug contains directly the antibiotic of the penicillin group, as well as clavulanic acid. Why add this ingredient in the manufacture of medicine? The fact is that clavulanic acid improves the penetration of the shells and helps the antibiotic better to cope with its task. The basis of the action of this substance is that it is introduced into the bacteria shells and the synthesizing of some amino acids and proteins ceases. Thanks to this, bacteria molecules are destroyed, clavulanic acid improves the interaction, as well as the penetration of the antibiotic into intercellular membranes.
As for the reception of this tool, there are a lot of contraindications. The fact is that when taking the medicine, it can very often manifest: dysbiosis, as well as thrush, the spread of fungi on the mucous membranes. Often occurs after taking antibiotics vaginal candidiasis, intestinal dysbiosis. In children there is candidiasis or stomatitis, which is provoked by the presence and growth of Candida fungi on the mucous membranes of the mouth.
Amoxiclav: take before or after eating?
In order to minimize the effect of the antibiotic on healthy cells and prevent the occurrence of the above situations, it is recommended to take it correctly. In order for this medicine to affect the state of health and flora of the intestine, it is recommended that you take antibiotics directly during meals.
It is unacceptable to take them before meals, as well as an hour after eating. Because at this time the intestines and stomach are semi -empty, which enhances the effect of the antibiotic and provokes the destruction of healthy microflora of the stomach and intestines. Accordingly, it is permissible to drink this medicine only when eating.
Indications for the use of amoxiclav
It is worth noting that the antibiotic is effective against gram -positive and gram -negative bacteria.
Basically, this medicine is prescribed for the treatment of such pathologies:
- Upper respiratory tract infections
- Chronic rhinitis
- Sinusitis
- Abscess
- Tonsillitis
- Pharyngitis
- In addition, they are used to treat the urinary tract and some infections in gynecology
- It is advisable to use an antibiotic in the case of a bite of wild animals in order to prevent tissue infection
- Prescribed for cholecystitis and cholangitis
Amoxiclav: Interaction with other drugs
It should be noted that this antibiotic is quite effective and interacts with some substances and drugs, forming compounds harmful to health. Accordingly, it is worth taking this drug with some of the drugs with caution. Basically, you need to be very careful when using diuretics, as well as non -steroidal anti -inflammatory drugs.
The fact is that these substances increase the concentration of amoxicillin, while clavulanic acid remains in the previous ratio. Accordingly, because of this, the effectiveness of the antibiotic is reduced, but the number of contraindications increases. The risk of colpitis, as well as dysbiosis and candidiasis, increases.
Vitamin C, ascorbic acid increase the absorption of antibiotic. You can not use a medicine with allopurinol, since because of this, strong allergic reactions in the form of skin rashes, trophic ulcers, as well as wet wounds may occur. Therefore, if you use any other drugs, it is necessary to use them separately from amoxiclava. This medicine is used only when eating, and the rest 2 hours before or 2 hours after eating. Thus, it will be possible to minimize the negative effects of the antibiotic on the body.
Other antibiotics that are used with amoxiclav at the same time reduce its actions. Accordingly, we recommend that for the period of amoxiclava treatment, refuse to use other antibiotics, because it can be harmful to health and increases the risk of side effects.
How to take amoxiclav: dosage
Regarding the dosage, on average, one tablet is prescribed, which contains 250 mg of antibiotic, every 8 hours. Accordingly, you will have to take them 3 times a day. If there is a very severe infection, then it is prescribed 500 mg three times a day.
If the patient has a violation of the liver function and kidneys, then it is recommended to reduce the concentration, as well as the amount of antibiotic taken, depending on the clinical characteristics of it in the blood and urine. It is worth remembering that the drug is not prescribed for children under 12 years of age and weighing less than 40 kg.
Amoxiclav: Contraindications
Typically, the antibiotic is absorbed and absorbed well, but there are contraindications to use, including allergies to penicillins and cephalosporins.
Contraindications:
- You can not take the drug for jaundice, as well as more serious liver disorders. Because the drug increases the load on this organ.
- You can not be prescribed to patients with severe kidney disorders.
- The drug is not prescribed for children under 12 years of age, the weight of which is less than 40 kg.
- Also, the drug is contraindicated in infectious mononucleosis and lympholecosis.
- It is worthwhile to use the medicine during pregnancy, as well as lactation. It was established that the medicine penetrates through the placenta and can provoke the development of serious developmental disorders in the fetus. Accordingly, this antibiotic is extremely rarely prescribed for pregnant women.
- You can not use the drug when breastfeeding, because a large amount of amoxiclav is released with breast milk. In addition, traces of clavulanic acid in milk were found, but in a small amount. Despite this, it is forbidden to use the drug during lactation. It is necessary to express milk and pour it.
If there is colitis, then you should be prepared for the fact that it can worsen when taking an antibiotic. For diseases of the gastrointestinal tract, it is worthwhile to use the medicine with caution. Because very often the exacerbation of ulcers and gastritis is fixed.
As you can see, the antibiotic should be used with caution, take it during food. This is a very important condition for its effectiveness, as well as to reduce the risks of developing side effects.
Video: Amoxiclav
